Description
Product Characteristics: For quantitative detection of TBX3 in serum, plasma, tissue homogenates.
Target Information: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms\, however, the full length nature of one variant has not been determined. [provided by RefSeq, Jul 2008]